Tuesday, August 14, 2012

Protandim Supplement Review

Since Protandim came out to the market in 2005 it has become a popular natural antioxidant. The benefits and studies of Protandim have its roots on Free Radical Biology, which is why there are so many studies that focus on this one supplement.

Most companies out there don’t perform any studies on their supplements but instead use what’s known as “borrowed science”, meaning they will use studies done with similar supplements to make claims on their own.

What is Protandim?

  • protandim-ingredientsCombats oxidative stress through a Nrf2 activation process.
  • Oxidative stress happens to everyone since free radicals are created when we eat, sleep, breath, exercise..
  • Protandim helps significantly reduce oxidative stress through a Nrf2 activation process.
  • Nf2 also helps regulate survival genes. These genes enable cells to survive when they come in contact with free radicals and other oxidants that promote aging and inflammation.
Protandim is made with natural herbal ingredients that include, Milk thistle extract, Bacopa extract, Ashwagandha, Turmeric Extract and Green Tea extract. The formula in Protandim has been patented, scientifically tested and researched in renowned universities institutions in the United States.

Protandim is the only supplement in the market clinically proven to reduce oxidative stress by up to 40% in 30 days.

What Makes Protandim Different?

protandim-newhttp://www.mylifevantage.com/432168/ 

Protandim can naturally increase the production of antioxidants enzymes like Superoxide Dismutase, CAT and Glutathione. These enzymes help protect the body from free radicals that cause further DNA damage.
Deterioration of DNA and rusting from the inside out is the primary cause of aging and other related degenerative diseases. Protandim protects the body, nurturing the skin at the cellular level.

As we age the body loses the ability to produce antioxidants causing free radicals to accumulate in the body. These process damages cells and causes skin deterioration and aging.

Antioxidants are the primary line of defense the body uses against free radicals. This is why is important to maintain levels of antioxidants in the body high, either with supplements, super foods or high antioxidant foods.

Unfortunately an average diet lacks foods rich in antioxidants, since most people don’t eat a full organic diet.

 

How Does Protandim Work?

According to several clinical studies done with Protandim, the antioxidants produced can reduce aging and deterioration by up to 40%. Unlike most conventional supplements that slowly reduce free radicals on a 1 to 1 basis, Protandim opens the gates to a flow of antioxidants to protect the body 24/7.

So far protandim holds more than 20 peer reviews, 4 patents and clinical studies in some of the best Universities around the country:
  • Harvard Medical (DMD)free-radicals-protandim
  • University of Florida
  • Glamorgan University, Wales
  • University of Kentucky
  • University of Minnesota (Diabetes)
  • Vanderbilt University
  • University or Toronto/St. Michelle’s Hospital, Canada
  • Virginia Commonwealth University (Heart Disease)
  • Michigan State University (Diabetes?)
  • University of Kentucky
  • University of Colorado
  • Louisiana State University (Cancer)
  • University Hospital, Brno, Czech Republic
  •  Mexican Institute of Social Security, Mexico City
  • Sahigrenska University Hospital, Goteborg, Sweden
  • Ohio State University
To put to rest any doubts about the validity of Protandim is a good idea to check out PubMed.org and search for studies under the keywords “Oxidative Stress” and “Protandim” there are over 8,000 peer review studies documented on PubMed about the supplement.

Protandim has many benefits including:
  • The ability to neutralize free radicals.
  • Reduce oxidative stress
  • Helps increase levels of Glutathione in the body by 300%
  • Helps increase levels of Catalase in the body by 54%
  • Helps increase levels of SOD in the body by 34%.
SOD and Catalese are powerful antioxidants enzymes produced by the body that play an important role on a healthy skin and body.

Many people have heard of antioxidants but hardly know how they work in the body and why we need them.

Antioxidants help the body fight internal rusting caused by particles that we know as free radicals. They are what the body uses as the primary line of defense against free radicals. Some doctors recognized aging to be the caused of rusting from the inside out .

Oxidation is caused by the accumulation of free radicals, leading to wrinkles and skin problems. Free radicals can damage DNA causing aging and other related diseases.

 

Protandim Studies

Protandim holds several studies in some of the most prestigious Universities in the U.S. You can download the PDF file to learn more about each study.

Anti- Aging and Oxidative Stress Study – Several studies on Protandim show the supplement to reduce oxidative stress by up to 40%.- University of Colorado.


Skin Care Study – Protandim helps reduce skin tumors by 33%. Louisiana State University

Heart Disease and Cardiovascular Study – Protandim helps enhance heart functions promoting a stronger cardiovascular system- Virginia Commonwealth University (Heart Disease)


Nrf2 Activator Study – Protandim is recognized as a Nrf2 transmitters, helping switch ON protective genes in the body- Virginia Commonwealth University


Muscular Dystrophy Study – Protandim helps reduces oxidative stress in muscular dystrophy.


Protandim Glutathione Study– Protandim helps increases levels of Glutathione in the body by 300%.
Watch the video below to learn more. You may also visit PubMed.org and search for the keywords “oxidative stress” or protandim” to find out more about studies with the supplement.

 

Protandim reviews

  • protandum reviews
  • protendum
  • potendim
  • research clinical case of antioxidants
  • WHAT IS BEING SAID ABOUT PROTANDUMS USEFULLNES
  • Does Protandim Really Work
  • protandin antioxidant reviews
  • what is the herbs protandim?
  • can you make your own protandim
  • aging the bodyproduces less enzymes

 

Protandim Clinical Studies

August 1, 2012
Protandim is a supplement that increases the daily production of antioxidants in the body. There are several clinical studies and peer reviews where Protandim has been the main subject.

 

Protandim Clinical Studies

Unlike most supplements in the market that use “Borrowed” science to support their claims, the studies done with Protandim actually mention the name of the supplement on each trial.
alternate text Before And After Images - 60 Days Of Use
Protandim is considered an anti-aging supplement since antioxidants are commonly used to destroy free radical accumulation in the body. These free radicals interfere with our DNA, damage cells, cause skin problems and other diseases related to aging.


The body produces less and less antioxidant, as we get older. Is key to take an antioxidant supplement, especially if we are not following an all-organic diet.


People, who are somewhat confused about the performance of Protandim, can refer to the different clinical studies, which explain how Protandim works in the body to fight different diseases.


Many reputed and renowned universities are associated with Protandim clinical studies. They have conducted medical trials to see how Protandim works to boost health.

Clinical Studies Showing the Efficiency of Protandim

Protandim is made with natural herbal ingredients that work synergistically to increase the levels of antioxidants in the body.


Being a combination of major herbal extract like milk thistle extract, bacopa extract, ashwagandha extract, green tea leaf extract and turmeric extract, Protandim works to reduce the damage incurred by oxidative stress and build a strong immune system.


Studies on Protandim emphasized the supplement to have all the capabilities to protect and provide, good overall health.


Find a short overview on some of the studies done with Protandim below.


Anti-aging & Oxidative Stress Study – According to the study protandim helps reduces oxidative stress by 40% - University of Colorado


The University of Colorado conducted a trial to see the effect of protandim on oxidative stress. Oxidative stress is considered as the main culprit for initiating the aging process in human.


Researchers involved twenty-nine human participants who were aged between 20 and 78. The participants were on a particular dose of this dietary supplement. A capsule of 675 mg was provided to them once daily.

The result was encouraging. The research result showed a statistically significant increase of SOD and catalase activity. These two are very important antioxidant enzymes, which destroy and counteract the effect of free radicals. Protandim works in the body as an antioxidant enzymes stimulator, essential to fight dangerous molecules known as free radicals.


Skin Cancer Study – Protandim helped reduce skin tumors by 33%. Louisiana State University.

Heart Disease And Cardiovascular Study – Protandim has been found to promote optimal heart function – Virginia Common Wealth University.


After years of research free radicals were found to harm some of the most important organs in the human body - brain cells and heart.


Free radicals weaken and damage healthy cells of the heart increasing the risk for heart failure. Researchers from Virginia Commonwealth University conducted a test to see how Protandim can reduce the harmful effect of the free radicals and they found a positive result.


Nrf2 Activator Study – Protandim helps activate Nrf2 transmitters to turn protective genes ON - Virginia Commonwealth University.


Muscular Dystrophy Study – Protandim reduces oxidative stress and improves muscular dystrophy.


Glutathione Study – Studies with Protandim, demonstrated the supplement to increase Glutathione by 300%


From all studies it can be said Protandim is a great supplement to slow down the damage aging causes in the body. It works by encouraging healthy aging and overall better health.
 
Read More

 

Protandim As A Natural Antioxidant

July 5, 2012
Aging is inevitable for everyone. It is the result of oxidative stress caused by free radicals that are obtained from daily activities such as breathing, eating, exercising, and everything in between. But with the help of a new scientific breakthrough, a new product called Protandim can help you delay the progressive aging process. Protandim is actually composed of natural plant ingredients.

This clinically proven product is patented and has been tested by various prestigious universities and other science and technology institutions. It is known as the best anti-aging supplement that has been proven to decrease oxidative stress in just 30 days.

Protandim Ingredients - Turmeric Extract

turmeric-protandim-supplementTurmeric is one of the essential ingredients of Protandim. It is found from the root of Curcumeric longa plant, which is widely available in Southern India and Indonesia. Turmeric is commonly used as a remedy for various health diseases. Needless to say, it has a lot of health benefits to offer.

What Are The Benefits Of Turmeric and Protandim?

Promotes Proper Digestion – Turmeric promotes proper digestion by improving your metabolism while maintaining your normal intestinal flora. It also prevents bloating while improving your body’s ability to absorb and digest fats.


Anti-Aging Properties – Turmeric helps cleanse your liver by making your liver function at its best so that it eradicate toxins the body. It also helps to increase the flow of bile so that the body can flush out toxins and free radicals. These free radicals are the main cause of aging. With a healthy functioning liver, the body can eradicate deadly toxins and free radicals to keep you looking younger and feeling healthier.


Anti-Cancer Properties – One of the best health benefits of turmeric is its ability to fight cancer cells. It actually helps your body inhibit the process of transforming healthy cells into tumor cells. More so, it effectively deteriorates mutated cancer cells in order to prevent spreading active cancer cells throughout the body.

 

Protandim Ingredients - Turmeric as an Essential Nutrient

Aside from Turmeric, Protandim also contains other essential vitamins and minerals that are needed by the body and come with their own set of health benefits. Protandim is indeed a great product for everyone, especially those who are suffering from serious health disorders and other kinds of diseases. Another great thing about Protandim is that it also has the capability to increase the glutathione levels in the body.


Glutathione is one of the most important components of the immune system. It helps boosts your immune system to make your body healthier and much stronger than before. Thus, the higher the amount of glutathione present in the body, the lesser the risk of acquiring various health diseases as it fights harmful cells and prevents certain diseases. This product has been clinically tested and proven to be both safe and effective for regular use. So if you want to achieve overall health and wellness, you will never go wrong with Protandim.
Read More

Protandim Ingredients

February 29, 2012
Protandim is a powerful antioxidant supplement. Antioxidants are the first line of defense the body uses against free radicals, which we inevitably accumulate with everyday life.

Protandim Blend Of Natural Antioxidants

Free radicals are unstable molecules. Usually the body can handle free radicals but if the we lack antioxidants or if free radicals become excessive they can cause inflammation and other diseases.

protandim-ingredientsInflammation can lead to diseases in the body such as acute coronary syndrome, arteriosclerosis, intestinal blooding, and many side effects that come with aging.

Many doctors, including nationally recognized anti-aging expert Dr. Joe McCord agree that aging and multiple degenerative diseases are the result of cell deterioration, caused by the accumulation of free radicals in the body.


Most antioxidant supplements in the market fight free radicals on a 1 to 1 ratio, meaning one free radical for every one antioxidant. Supplements like Protandim on the other hand increase the production of antioxidants in the body, creating a cascade of Antioxidant enzymes such as Super Oxidate Dismutase, CAT and Gluthatione. Free radicals are everywhere, they can come from the air we breath, the food we eat and even the stress we deal with every day in our life. This is why is best to protect the body with Protandim.


As we get older the body produces more free radicals and less antioxidant enzymes making it almost impossible to win the battle with aging.

This is where Protandim comes in place and has many positive effects. Protandim helps boost the production of antioxidant enzymes at a cellular level, therefore helping reduce the harsh effects that aging can have in the body.

What Are The Ingredients In Protandim?

Protandim Ingredients were carefully chosen to help regulate and preserve the natural antioxidants produced by the body including Gluthatione, CAT and Super Oxide Dismutase.
The herbal blend in Protandim includes :
  • Bacopa Extract

  • Ashwagandha

  • Turmeric Extract

  • Green Tea Extract

  • Milk Thistle Extract
Every herbal extract in Protandim formula was chosen because it helps increase the production of antioxidants. When combined the ingredients act synergistically to produce even more antioxidant power.

Protandim is made with all natural ingredients, and yes you can get each one of these natural ingredients at a health food store for example but don’t expect to get the same results and the antioxidant benefits you can get with the supplement.

 

Protandim Ingredients Are The Key

Even thou you could buy the ingredients in Protandim individually, you will never get the same results by simply combining these ingredients.


The reason you will not get the same benefits is because the herbal blend in Protandim is literally a recipe. There are 5 ingredients in Protandim, but is the percentages of each ingredients that counts.


Similar for example, to bread which also has 5 ingredients. If you take flour, butter, egg, milk and yeast and add them together in any proportions, you may or may not get bread. Is that certain proportion and percentage that gives you the right outcome.


In the case of Protandim, the outcome that we are looking for when mixing all these ingredients is the antioxidant benefits,and you can’t get these benefits by adding all ingredients together in whatever percentage.


February 29, 2012
Protandim is a powerful antioxidant product that promises to slow down the rate of aging by 40%. There are many companies in the MLM industry but its rare to see one with so many credentials and studies as Protandim has. The name of the company is life advantage and the product name is Protandim. protandim reviewshttp://www.mylifevantage.com/432168/ Life advantage started out under the name of LifeLine Therapeutics and later change the original name to Life Advantage. Initially Paul Myhill started the company. In late 2004 Dr. Joe McCord started to perform clinical studies on humans to further analyze how Protandim helps reduce oxidative stress. In late 2005 studies were approved to be publish in the FRBM ( Free Radical Biology Medicine) journal. After successful studies came out, Protandim was feature on ABC, PBS and the Today Show. The product became really popular, but it wasn't popular enough to sustain the company. Which is why in 2009 Life Advantage change their original business model of distribution to an MLM network-marketing model.

Protandim Supplement Review

Protandim is a powerful antioxidant that has had extensive clinical research, and studies over the last 7 years. More than 20 universities have started studies to see how Protandim works to prevent aging and others side effects of oxidative stress. Many of the studies were complete successfully and the details and results can be founding www.pubmed.gov, when you research the keyword "protandim". Life advantage has real approve studies behind its product, which serve as validation of the claims that Protandim works. Protandim sets itself apart from many traditional antioxidant supplements. What Protandim does, is stimulate the body's natural production of enzymes, including SOD and CAT. The enzymes produced are use by the body to destroy Free Radicals. Clinically studies have shown the production of these enzymes to be the most effective way to eliminate and fight free radicals. So how great is the company behind Protandim? There is not one reason to believe LifeAdvantage is not a real and solid company, with what can be a life chanting product line. As a company life Advantage offers a great compensation plan that can benefit anyone with some experience and without to get started and promote the products for a decent income. Additionally the many studies and information behind the product, make it easy for anyone involved with the business to how their customers and sell. Life Advantage offers great training for distributors to promote the products. The training the company provides is basic, and that’s understandable because at the end they are in the business of making product that shows real results and works. WE as distributors are in the business to promote and sell their products. So is Protandim a Scam? The answer is NO. Protandim is of course not a scam; you can make a really great income if you know how to build a business and take advantage of their amazing product line.
Read More

What is Protandim?

May 10, 2011
When it comes to searching for a good supplement it can almost be overwhelming, since there are so many reviews and information online. Because of such information overload is best to stick to the facts and choose a supplement that has been properly tested.

protandim reviews
Unfortunately it can be hard to find a supplement that holds any kind of studies.


Yes, There are a lot of supplements online with some kind of research. But usually the research is focus on the ingredients rather than the actual finished supplement. Protandim on the other hand sets itself apart from any supplement, since the research actually mentions “Protandim” as the main subject of the studies.


Currently Protandim holds over 10 peer reviews, in some of the most prestigious Universities around the country. If that wasn’t enough there are over 20 institutions conducting studies on the benefits of Protandim for several diseases.

Protandim Clinical Studies

Protandim holds several studies and peer reviews in some of the best and renowned universities in the U.S:
  • Harvard Medical (DMD)

  • University of Kentucky

  • Michigan State University (Diabetes)

  • University of Kentucky

  • University of Colorado

  • Louisiana State University (Cancer)

  • University Hospital, Brno, Czech Republic

  • Glamorgan University, Wales

  • University or Toronto/St. Michelle’s Hospital, Canada

  • University of Florida

  • University of Minnesota (Diabetes)

  • Vanderbilt University

  • Virginia Commonwealth University (Heart Disease)

  • Mexican Institute of Social Security, Mexico City

  • Sahigrenska University Hospital, Goteborg, Sweden

  • Ohio State University

What is Protandim?

The process of aging starts with every cell in the body. Generally it was thought the process of aging was inevitable and progressive, but research studies have proved otherwise.

Protandim is a breakthrough product that has been clinically proven to slow down the aging process at the cellular level.

Protandim Studies have shown aging and other degenerative diseases to be the result of deterioration cause by rough molecules, known as free radicals. The damage free radical causes in the body is known as Oxidative stress. This unique supplement works by increasing the production of antioxidants to fight free radicals on a daily basis.

How Does Protandim Work?

protandim-reviewsProtandim is a powerful supplement that gives you a better way to fight the free radicals that cause aging. The supplement has been clinically proven to reduce Oxidative damage by 40%, which in turns helps slow down the aging process at a cellular level to the one of a 20 year old.

Protandim is not your regular antioxidant supplement. Each capsule of Protandim contains a unique blend of phytonutrients that sends the body signals to increase the production of antioxidant enzymes. Antioxidants are the fist line of defense the body uses to fight free radicals.

The reason why Protandim works so well lays on the combination of ingredients that makes up the supplement. The blend in Protandim contains 5 ingredients including Milk Thistle, Bacopa, Green Tea, Turmeric, and Ashawagansha. Each one of the ingredients in Protandim plays a role on increasing the production of antioxidants.

We can’t escape the damage of free radicals:

Free radicals are the molecules that cause rust. In a way, aging can be defined as the rusting of the body from the inside out. The body naturally creates free radicals when we:
  • Breathe toxins in the air.

  • Have any kind of stress in life.

  • Drink, smoke or take prescription drugs.

  • When we exercise drastically.

  • Even when we expose the skin to the sun.
The ability for the Body to fight aging decreases, as we get older.

When we are young our body is full of life and is capable of producing antioxidants on its own. As we get older the body produces less antioxidants and is harder for it to fight disease.

Even foods that are Rich in Antioxidant can’t prevent the body from Free radicals.


Protandim is a powerful natural supplement, which contains more antioxidant power than any food or supplement in one capsule.


It was estimated than to get the same levels of antioxidants in Protandim you’ll have to drink 87 glasses of red wine, and 375 oranges, this is about 120 capsules of vitamin C tables (500mg) every day to minimize the effects that free radicals have in your body daily.


Not all antioxidants are made equal. Most antioxidant supplements such as vitamin A, C and E are popularly known as “consumable” and unlike Protandim are not powerful enough to help the body produce special antioxidant enzymes such as CAT and SOD.


These special enzymes work together to defend the body against any free radicals. Unlike conventional antioxidant supplements SOD and CAT are not used up once they neutralize free radicals. One single capsule of Protandim, creates lots of body’s natural catalytic antioxidants that help destroy millions of free radicals per second.

Thursday, June 7, 2012

The Business Opportunity

If you wish to be involved in this business opportunity and partner with us.....

ID 432168
* You will need this number 432168 for the Enroller and Placement verifications when you proceed to the application.
_____________________________
If you live in the US, Mexico or Canada please click here
_________________________________

If you live in other countries please contact Audra at: audracaputo@gmail.com
_________________________________

If you live in any country not mentioned please contact Audra.

Below is Gabe Pearson and Mark Simpson talking about inviting people to look at this business opportunity!

How Good is the LifeVantage opportunity?

Who Needs Protandim?

Who Would Need Protandim and Why ?

If you are interested in a business opportunity contact the person who sent you here, or email Audra @ audracaputo@gmail.com

Protandim: The Clinical Proof

On November 18, 2008, the results of a new peer-reviewed study (Free Radical Biology & Medicine) clearly demonstrate that Protandim produces a 300 percent increase in glutathione, which is a key antioxidant and anti-aging factor.

In addition, the study shows that Protandim’s synergistic formulation provides thousands of times more antioxidant power than any food or conventional supplements. Click here to view the study:  protandim-study Synergistic induction of heme oxygenase-1 by the components of an antioxidant

In an August 2005 published, peer reviewed human study, Protandim has been shown to eliminate the age-related increase in cell aging factors* Dr. Joe McCord, a world renowned scientist, validated the precise combination of natural phytonutrients in the patented Protandim formula and proved that Protandim consistently and significantly boosted the body’s own production of two crucial protective antioxidant enzymes, SOD (superoxide dismutase) and CAT (catalase).* The implications were profound because these two antioxidant enzymes play a major role in neutralizing the cell-damaging free radicals associated with aging and a variety of health conditions.

Protandim is not an antioxidant supplement. It helps your body produce its own antioxidants with thousands of times more antioxidant power than any food or conventional supplement.* And the proof is conclusive.

Aging factors can be measured accurately by the amounf of TBARS (thiobarbituric acid-reactive substances) found in the blood. In clinical trials with men and women, young and old, the blood samples consistently demonstrated that after 30 days, taking one caplet a day, test subjects realized a 40 percent average decrease in TBARS - the progressive aging rate of a 20 year old!

When maintained for 120 days, Protandim significantly increased activity of SOD and CAT antioxidant enzymes by 54 percent, substantially increasing the body’s antioxidant defenses.*

Some Test results

Picture
The RED LINE represents normal, healthy test subjects BEFORE taking Protandim, Many of the subjects were taking antioxidant supplements. The clinical study clearly showed that the aging factors (TBARS) steadily increased with age at a predictable rate, even with conventional antioxidant supplementation.

The GREEN LINE represents test subject AFTER taking Protandim for 30 days. As you can see, the aging factors as measured by the presence of TBARS in the blood, decreased an average of 40% among virtually all test subjects, regardless of their age.

Nrf2 .....  Hear from the scientist himself about of what Protadim does.... 
This is amazing technology isn't ?
 If you are interested, contact the person who sent you here, or email
Audra at; audracaputo@gmail.com
http://www.mylifevantage.com/432168/

Oxidative Stress - why is it so bad?

Oxidative Stress:

Oxidative stress, simply put, is the damage made to a cell through the oxidative process.

Oxidation, in itself, is a very normal process - it happens all the time to our bodies and many things that surround us.

However, when there are disturbances in the natural oxidation process, such as the attraction of a free radical to another molecule in your body, the results are often toxic effects.

Imagine an iron pipe lying on the ground. As it weathers years of rain, environmental exposure, sun, and other factors, it begins to rust.

The rust is caused by oxidation. Free oxygen radicals are created during the metabolism of normal oxygen cells, or oxidation. These free radicals are missing a simple electron and are in search of another molecule that they can combine with to become "whole." In their quest, they fire charges that damage other cells and structures around them. This, in turn, causes the rust.
In effect, your body is "rusting" as it goes through its lifetime, the free oxygen radicals wildly running through your system, searching for a mate.

As you can see, the more free radicals your body contains, the more damage that's likely to be done. The best way to see this damage is through our normal aging process.
 
* Cancer results as the chain damages cell membranes and DNA.
Oxidative Stress and Aging


While modern medicine has found ways for humans to live longer, our quality of life - especially during the last 30 years - has gone down.
Much of this can be attributed to oxidative stress and the toxins that we're encountering more and more throughout our lives.
A simple way to visually experience the effects of oxidative stress on aging is to visit a nursing home. Compare the skin of a five-year-old to that of a resident, and notice the breakdown, wrinkles, and color as compared to the smooth, supple skin of a child.
Throughout our lives, our skin encounters free radicals in many different forms, and their effect is clearly obvious on our skin.
But oxidative stress isn't only apparent on the outside. It's the cause of many or most diseases our society is concerned with today.
Oxidative Stress and Disease


To date, science has discovered that oxidative stress may very well be the cause of over 70 well-known, widely-spread diseases.
Depending on what form of toxin or stress your body is exposed to on an ongoing basis, you could find yourself suffering, even at an early age, from diseases that could be prevented if only you'd have minimized the harmful free radicals in your system.

WHAT IS A FREE RADICAL & WHAT DOES IT DO?

WHAT IS A FREE RADICAL & WHAT DOES IT DO?
 
For many years the existence of free radicals in biological systems was dismissed as either non-existent or simply an unimportant curiosity. However, more recently due to improved investigational techniques, this view has changed rather dramatically. Currently, free radicals have found a place in the aetiology of many diseases and there is a great deal of enthusiasm regarding the role of free radicals in many previously unexplained disease phenomena. To name a few important areas; free radicals have found a role in the rheumatoid arthritis, Alzheimer's disease, hypertension, myocardial ischemia, liver cell injury and carcinogenesis.


The reason as to why the role of free radicals has been so ambiguous is probably due to their ultra-short half-life. However, free radicals have finally come into existence through the use of more sophisticated methods of assay.

The fact that they are highly reactive means that they have low chemical specificity; i.e. they can react with most molecules in its vicinity. This includes proteins, lipids, carbohydrates and DNA. It also means that in trying to gain stability by capturing the needed electron they don't survive in their original state for very long and quickly react with their surroundings. Hence, free radicals attack the nearest stable molecule, "stealing" its electron. When the "attacked" molecule loses its electron, it becomes a free radical itself, beginning a chain reaction. Once the process is started, it can cascade, finally resulting in the disruption of a living cell.

Antioxidants are molecules which can safely interact with free radicals and terminate the chain reaction before vital molecules are damaged. Although there are several enzyme systems within the body that scavenge free radicals, the principle micronutrients cannot be processed fast enough to keep up with these free radicals that are occurring each second of the day.  This happens more and more as we age, so in effect, our bodies own aging causes the advancement of harmful free radicals and then the free radicals cause us to age faster and over 200 diseases are tied to free radicals so far. 
This is when Protandim comes into play.

The two most important oxygen-centered free radicals are superoxide and hydroxyl radical. They are derived from molecular oxygen under reducing conditions. However, because of their reactivity, these same free radicals can participate in unwanted side reactions resulting in cell damage. Many forms of cancer are thought to be the result of reactions between free radicals and DNA, resulting in mutations that can adversely affect the cell cycle and potentially lead to malignancy. Some of the symptoms of aging such as atherosclerosis are also attributed to free-radical induced oxidation of many of the chemicals making up the body. In addition free radicals contribute to alcohol-induced liver damage, perhaps more than alcohol itself.  Radicals in cigarette smoke have been implicated in inactivation of alpha 1-antitrypsin in the lung.  This process promotes the development of emphysema.

Free radicals may also be involved in Parkinson's disease, senile and drug-induced deafness, schizophrenia, and Alzheimer's. The classic free-radical syndrome, the iron-storage disease hemochromatosis, is typically associated with a constellation of free-radical-related symptoms including movement disorder, psychosis, skin pigmentary melanin abnormalities, deafness, arthritis, and diabetes mellitus.

Science Driven!


Scientists agree that aging and many deadly diseases are the result of cellular deterioration due to rogue molecules called free-radicals .

Free-radical damage is known as Oxidative Stress or Oxidative Damage. Protandim fights the free radicals that cause aging!

PROTANDIM is the only supplement clinically proven to reduce oxidative stress by an average 40%, slowing down the cell aging process to the level of a 20 year-old.* Protandim is not a conventional antioxidant supplement. Each Protandim caplet contains a unique combination of phytonutrients that signal the body’s genes to produce its own antioxidant enzymes, which provides thousands of times more antioxidant power than any food or conventional antioxidant supplement.

A Look at Free Radicals

Obviously, even back in the early days of man, free radicals existed and caused oxidative stress.
They're inherent to life and a normal byproduct of regular oxygen molecule metabolism. However, our bodies were only made to withstand so much exposure to free radicals (even though our body does an amazing job at neutralizing them in a normal, low-toxin setting).
The increased and prolonged exposure to these wild and reckless free radicals cause a faster build-up of "rust" or disease in our bodies.
So what are some of the most common reasons our bodies' oxygen molecules oxidize themselves into an increased amount of free radicals? Some of them you're probably well aware of, and some of them may come as a surprise.

  • Environmental & Air Pollution
  • Cigarette Smoking
  • Excess Stress
  • Prescription & Over the Counter Medications
  • Radiation
  • Increased Exposure to Sunlight
  • Excessive Exercise

THE REAL STORY ON FREE RADICALS.

 
Very few individuals, if any, reach their potential maximum life span; they die instead prematurely of a wide variety of diseases--the vast majority being "free radical" diseases.

--Denham Harmon, M.D., Ph.D., who in 1954 first proposed the Free Radical Theory of aging


Honey, take a look at this. You might find it interesting."

Great moments in human history often begin inauspiciously. Such was the case in December 1945, when the wife of Denham Harmon handed him the latest issue of the Ladies' Home Journal.  It was opened to an article titled "Tomorrow You May Be Younger," written by William L. Laurence, science editor of the New York Times.  This article, heralding the work of a Russian gerontologist on an "anti-reticular cytotoxic serum," sparked Dr. Harmon's interest in finding an answer to the riddle of aging--a subject that scientists of the time knew absolutely nothing about.   Even to this day most MD’s know very little about Free Radicals/Oxidative Stress.

For the next nine years, Dr. Harmon, a brilliant young organic chemist with a Ph.D. from the University of California, Berkeley, ruminated about the aging process.

Because aging is such a universal phenomenon, he reasoned that it might have a single basic cause. But what could it be?  The answer eluded him.

Though still obsessed with the question, he had to place it on the back burner while he completed medical school and an internship at Stanford University.  Then one morning in November 1954, during a period in which he was simultaneously completing his residency in internal medicine and doing research at Berkeley's Donner Laboratory, Dr. Harmon's quest ended.  That day, while reading in his office, he had an "aha" experience that would revolutionize medical science: "(It) suddenly occurred to me that free radical reactions, however initiated, could be responsible for the progressive deterioration of biological systems." of course, sometimes even the best ideas are slow to be accepted. This one didn't exactly inspire words of praise--not at first, anyway. After thinking it over for a month, Dr. Harmon strolled the Berkeley campus, knocking on doors and presenting his newly formulated Free Radical Theory to his colleagues. To say that it was a hard sell would be an understatement. He might have had more success had he been hawking vacuum cleaners.

The scientists whom Dr. Harmon approached were singularly unimpressed. In fact, all but two flatly rejected his idea. One after another, they slammed the door in the face of the young upstart, who dared challenge the status quo with the preposterous notion that all degenerative disease--and the aging process itself--could be explained by the presence of free radicals.

Undaunted, Dr. Harmon pursued his theory. In subsequent years, he demonstrated how the effects of free radicals are reversed by nutrients known as antioxidants, how antioxidants extend the life spans of laboratory animals, and how antioxidants offer protection against heart disease, cancer, senile brain disease, and all other degenerative conditions associated with aging. Dr. Harmon proved that age-related immune deficiency is caused by free radicals and can be reversed by antioxidants.

In terms of scientific significance, Dr. Harmon's Free Radical Theory ranks with Galileo's invention of the telescope, Newton's discovery of gravity, and Einstein's theory of relativity. No breakthrough has had more profound implications for human health and longevity.

Now in his mid-eighties and still professionally active, Dr. Harmon deserves the Nobel Prize for his revolutionary work.
 


Free Radicals: Longevity's Most Formidable Foe  
 Dr. Harmon's Free Radical Theory has emerged as the best understood and most widely accepted explanation of the aging process. Having stood the test of time and countless research validations, it has become not just a damage theory but the damage theory. (You'll recall from chapter 1 that according to damage theories, cumulative cellular damage determines a person's age of death.) In fact, among doctors specializing in anti-aging medicine, Free Radical Theory has transcended mere theory status and is considered a biological fact of life.

Just what are these free radicals, anyway? Understanding where they come from, and why and how they do so much damage, requires a brief lesson in biochemistry.

Molecules are made up of atoms glued together by chemical bonds. Each bond consists of a pair of electrons. When a bond is broken, what's left are two molecular fragments, each of which contains one of the now unpaired electrons. These molecular fragments are highly charged and highly unstable, because they contain only one electron rather than two. These highly charged, highly unstable, highly reactive particles are what we know as free radicals.

Unfortunately for us humans, the biochemical saga of free radicals doesn't end there. Remember, each free radical contains one unpaired electron. And unpaired electrons, like unpaired humans, hate to be alone. They want a partner, and they're not above breaking up another bond to get what they want. Scientists call this process oxidation, and free radicals are masters at it. They're not particularly discriminating about where they get their new partners, either. They'll oxidize just about anything that gets in their way--punching holes in cell membranes, destroying key enzymes, and fracturing DNA.

What's more, free radicals are remarkably prolific. One free radical, unchecked, can cause new ones to form. These free radicals, in turn, give rise to many more. How does this happen?

Because it has so much energy, a free radical zips about until it bangs into a nearby molecule with a stable bond.  The collision splits the stable molecule, releasing one of its two electrons.  The free radical nabs the electron as a partner for its own unpaired electron, and the two form a stable bond. All this happens, quite literally, within nanoseconds.

The good news is that the free radical has stabilized itself. The bad news is that in doing so, it may have caused the formation of two more free radicals by breaking a stable bond, leaving the two atoms of the formerly stable molecule to share one unpaired electron.  So begins a chain reaction that produces thousands of molecular fragments with unpaired electrons.  And every one of these fragments is careening about, looking to swipe an electron from an unsuspecting stable molecule.

To get a clearer understanding of how free radicals multiply, imagine a football stadium filled to the brim with mousetraps, each mousetrap loaded with a Ping-Pong ball.  If you drop one Ping-Pong ball into the stadium, it springs one mousetrap, causing it to fling its ball into the air.  Then you have two loose Ping-Pong balls, which spring two more mousetraps. Within a matter of seconds, all of the mousetraps are sprung, and all of the balls are loose.

Now if all those mousetraps were stable molecules, and all those Ping-Pong balls were free radicals, you would have just witnessed a free radical free-for-all.